Craig Mayer, Nick WIlliams, Vojtech Huser
Lister Hill National Center for Biomedical Communications, National Library of Medicine, NIH, Bethesda, MD

See the full regCTG repository at https://github.com/lhncbc/CRI/tree/master/regCTG

To return to the list of conditions and view other reports go to https://lhncbc.github.io/CRI/regCTG/regCTG-condition_report_links.html


Study Counts

Type Study_count
Total_Studies 180
interventional 153
Observational 26
Registry 1

Studies over Time by Start Date

```

Interventional Trials

Intervention Type

intervention_type Study_Count
Device 108
Procedure 28
Device|Procedure 8
Device|Other 3
Diagnostic Test 2
Other 2
Behavioral 1
Device|placebo 1

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Yearly studies for each intervention by start date

Studies by Country

Country Study_Count
United States 55
NA 30
United Kingdom 11
Austria 7
China 5
Mexico 5
Spain 4
Canada 3
Egypt 3
Germany 3
Korea, Republic of 3
Netherlands 3
Brazil 2
Iran, Islamic Republic of 2
Japan 2
United States|Canada 2
Austria|France|Germany 1
China|India 1
Colombia 1
Czech Republic 1
Denmark 1
France|Germany|Spain 1
Greece 1
Iraq 1
Malaysia 1
Mexico|Philippines 1
New Zealand 1
Sweden 1
United States|Australia 1

Sites per Study

Site_count Study_Count
1 118
2 11
3 4
4 4
5 2
6 2
7 1
8 2
10 1
12 2
13 1
14 1
17 1
18 1
20 1
23 1

Phase

Phase Study_Count
N/A 131
Phase 4 16
Phase 3 3
Phase 1/Phase 2 2
Phase 2 1

Number of Arms

Number_of_Arms Count_of_Studies
1 35
2 90
3 12
4 3
6 3
12 2
19 1
NA 7

Enrollment Metrics by Phase

Measure N.A Phase.1.Phase.2 Phase.2 Phase.3 Phase.4
Min. 4.0000 30.0 40 35.00 18.0000
1st Qu. 36.5000 37.5 40 38.75 40.0000
Median 60.0000 45.0 40 42.50 52.5000
Mean 110.2901 45.0 40 42.50 63.8125
3rd Qu. 120.0000 52.5 40 46.25 61.5000
Max. 1100.0000 60.0 40 50.00 198.0000

Trial Group Type

group_type Group_Count
Active Comparator 149
Experimental 133
Other 36
NA 7
No Intervention 3
Sham Comparator 2
Placebo Comparator 1

Intervention Model

intervention_model Study_Count
Parallel Assignment 63
Single Group Assignment 50
Crossover Assignment 39
NA 1

Primary Purpose

primary_purpose Study_Count
Treatment 121
Other 11
Diagnostic 6
Supportive Care 5
NA 5
Basic Science 2
Device Feasibility 2
Health Services Research 1

Observational Studies

Studies by Country

Country Study_Count
United States 13
NA 3
China 2
Austria 1
Belgium 1
Canada 1
Egypt 1
Germany 1
Korea, Republic of 1
Norway 1
Spain 1

Sites per Study

Site_count Study_Count
1 26

Enrollment Metrics

Measure Observational
Min 20.0
1st Qu 40.0
Median 56.5
Mean 332.0
3rd Qu 303.0
Max 4000.0

Observation Model

observational_model Study_Count
Cohort 14
Case-Only 4
Case-Control 2
Other 2
NA 2
Case-Crossover 1
Case Control 1

Time Perspective

time_perspective Study_Count
Prospective 18
Cross-Sectional 4
Retrospective 3
NA 1

Registries

Studies by Country

Country Study_Count
Turkey 1

Sites per Study

Site_count Study_Count
1 1

Enrollment Metrics

Measure Registries
Min 62
1st Qu 62
Median 62
Mean 62
3rd Qu 62
Max 62

Registry Model

observational_model Study_Count
Case-Control 1

Time Perspective

time_perspective Study_Count
Prospective 1

Follow-up

target_duration Study_Count
30 Months 1

Overview of Studies

Interventional Trials

#If less then 500 trials

nct_id brief_title link overall_status source primary_completion_date
NCT03392532 Comparison of Two Silicone Hydrogel Toric Contact Lenses https://ClinicalTrials.gov/show/NCT03392532 Completed Alcon Research 2018-01-26
NCT03350503 AcrySof IQ Toric A-Code Post-Market Clinical Study https://ClinicalTrials.gov/show/NCT03350503 Active, not recruiting Alcon Research 2019-05-23
NCT03819842 Evaluating the Need for the Pseudophakic Intraoperative Abberrometry in Toric IOL Implantation https://ClinicalTrials.gov/show/NCT03819842 Completed Alterman, Modi, & Wolter Ophthalmic Physicians & Surgeons 2019-01-14
NCT03313921 The MORE Study: Manifest vs. Online Refraction Evaluation https://ClinicalTrials.gov/show/NCT03313921 Active, not recruiting UMC Utrecht 2019-07-24
NCT03291873 Topography-Guided Customized PRK Versus Q-value Adjusted PRK in Correction of Myopia With or Without Astigmatism https://ClinicalTrials.gov/show/NCT03291873 Completed Kasr El Aini Hospital 2019-06-25
NCT03242486 Clinical Evaluation of Toric Intraocular Lens https://ClinicalTrials.gov/show/NCT03242486 Completed Nidek Co. LTD. 2017-05-31
NCT03202485 Comparison Between TICL and ICL+AK for High Myopic Astigmatism https://ClinicalTrials.gov/show/NCT03202485 Completed Wenzhou Medical University 2015-03-02
NCT03140046 Visual Outcomes of Topography Guided Photorefractive Keratectomy (PRK) for Treatment of Patients With Irregular Cornea https://ClinicalTrials.gov/show/NCT03140046 Completed Assiut University 2018-03-01
NCT03134248 Bilateral Dispensing Study of MyDay Toric, 1-day Acuvue Moist for Astigmatism, and Dailies Aquacomfort Plus Toric Lenses https://ClinicalTrials.gov/show/NCT03134248 Completed Coopervision, Inc. 2017-04-12
NCT03085901 Comparison of Clinical Outcomes of Toric Intraocular Lens https://ClinicalTrials.gov/show/NCT03085901 Completed Samsung Medical Center 2016-07-31
NCT03082599 Symfony Toric Intraocular Lens Visual Outcomes https://ClinicalTrials.gov/show/NCT03082599 Completed Carolina Eyecare Physicians, LLC 2018-04-03
NCT03063164 A Comparison of LASIK Outcomes Using Two Femtosecond Lasers https://ClinicalTrials.gov/show/NCT03063164 Recruiting Stanford University 2020-12-31
NCT03054649 ClarVista HARMONI Toric Trial With Intraoperative Exchange https://ClinicalTrials.gov/show/NCT03054649 Completed ClarVista Medical 2017-07-18
NCT03006458 A Clinical Comparison of 2 Multifocal Toric XR (Extended Range) Contact Lenses https://ClinicalTrials.gov/show/NCT03006458 Completed Coopervision, Inc. 2017-04-06
NCT02950545 Evaluating and Improving Functional Driving Vision of Patients With Astigmatism: Phase 3 https://ClinicalTrials.gov/show/NCT02950545 Completed University of Virginia 2017-02-01
NCT02939001 Evaluating the Effect of Laser Vision Surgery, Phakic Intraocular Lens Implantation, Cataract Surgery, and Pupil Dilation on the Iris Recognition Scanner Function of Smartphone https://ClinicalTrials.gov/show/NCT02939001 Completed Yonsei University 2017-03-24
NCT02921412 Performance of Fanfilcon A Toric Lenses After at Least One Month Wearing Enfilcon A Toric Lenses https://ClinicalTrials.gov/show/NCT02921412 Completed Coopervision, Inc. 2017-02-01
NCT02847169 Clinical Performance of Toric Hydrogel Contact Lenses Following One Week of Daily Wear https://ClinicalTrials.gov/show/NCT02847169 Completed Coopervision, Inc. 2016-11-30
NCT02801006 The Clinical Study of Silicone Hydrogel Daily Disposable Stenfilcon A Toric Lens https://ClinicalTrials.gov/show/NCT02801006 Completed Coopervision, Inc. 2016-06-30
NCT02763124 Pseudophakic Astigmatic Reduction With Verion-LenSx Arcuate Incisions https://ClinicalTrials.gov/show/NCT02763124 Completed Gainesville Eye Associates 2016-10-31
NCT02675751 Prospective S&E Study of Wavefront-guided PRK for Myopia With iDesign Advanced Wavescan Studioâ„¢ System and Star S4 IRâ„¢ https://ClinicalTrials.gov/show/NCT02675751 Completed Abbott Medical Optics 2018-07-27
NCT02649842 Post-Approval Study of the TECNIS® Toric Extended Cylinder Range Intraocular Lens (IOL) https://ClinicalTrials.gov/show/NCT02649842 Completed Abbott Medical Optics 2018-08-27
NCT02625220 Dispensing Evaluation of Investigational Contact Lenses https://ClinicalTrials.gov/show/NCT02625220 Completed Johnson & Johnson Vision Care, Inc. 2015-11-30
NCT02624791 Evaluating and Improving Functional Driving Vision of Patients With Astigmatism https://ClinicalTrials.gov/show/NCT02624791 Completed University of Virginia 2013-01-31
NCT02565537 High Resolution Wavefront-guided vs. Wavefront Optimized LASIK https://ClinicalTrials.gov/show/NCT02565537 Active, not recruiting Stanford University 2022-01-31
NCT03398109 Effectiveness of Toric Intraocular Lenses for Treating Corneal Astigmatism in Patients With Cataract and Previous DALK https://ClinicalTrials.gov/show/NCT03398109 Completed Fondazione G.B. Bietti, IRCCS 2017-06-29
NCT02551796 Early Changes Among FLEx, LASIK and FS-LASIK https://ClinicalTrials.gov/show/NCT02551796 Completed Sun Yat-sen University 2016-04-30
NCT02550353 Changes Between Lenticule Extraction and Femtosecond Laser-assisted Laser in Situ Keratomileusis https://ClinicalTrials.gov/show/NCT02550353 Completed Sun Yat-sen University 2016-03-31
NCT02540785 Early Changes Between Lenticule Extraction and Small-Incision Lenticule Extraction https://ClinicalTrials.gov/show/NCT02540785 Completed Sun Yat-sen University 2014-12-31
NCT02513745 Conventional Surgery vs. Verion/VerifEye https://ClinicalTrials.gov/show/NCT02513745 Completed Carolina Eyecare Physicians, LLC 2017-05-05
NCT02444923 Scleral Versus Corneal RGP Contact Lenses in Irregular Cornea Disorders https://ClinicalTrials.gov/show/NCT02444923 Completed London South Bank University 2019-01-29
NCT02430428 Correction of Myopia Wtih or Without Astigmatism Using the VisuMaxâ„¢ Femtosecond Laser https://ClinicalTrials.gov/show/NCT02430428 Completed Carl Zeiss Meditec, Inc. 2017-10-31
NCT02423109 Bilateral Dispensing Study of Fanfilcon A Toric Versus Enfilcon A Toric Lenses https://ClinicalTrials.gov/show/NCT02423109 Completed Coopervision, Inc. 2016-01-31
NCT02410824 Bilateral Dispensing Clinical Trial of Stenfilcon A Against Etafilcon A for Astigmatism https://ClinicalTrials.gov/show/NCT02410824 Completed Coopervision, Inc. 2015-06-30
NCT02370953 VERION Versus Conventional, Manual Ink-marking in Toric IOL Implantation https://ClinicalTrials.gov/show/NCT02370953 Completed Maastricht University Medical Center 2016-01-31
NCT02356692 Clinical Comfort Evaluation of Two Marketed Spherical Contact Lenses https://ClinicalTrials.gov/show/NCT02356692 Completed Coopervision, Inc. 2012-05-31
NCT02248766 Clinical Performance of Habitual Wearers of Avaira Toric When Refitted With Clariti Toric Lenses https://ClinicalTrials.gov/show/NCT02248766 Completed Coopervision, Inc. 2014-10-31
NCT02193178 Multicenter Dispensing Study of Biofinity Toric Made-To-Order Lenses in Extended Power Ranges https://ClinicalTrials.gov/show/NCT02193178 Completed Coopervision, Inc. 2016-04-30
NCT02185105 Clinical Validation of Biofinity Toric MTO (Made To Order) Lenses https://ClinicalTrials.gov/show/NCT02185105 Completed Coopervision, Inc. 2014-06-30
NCT02176343 Retrospective / Prospective Clinical Study of AcrySof® IQ ReSTOR® +2.5 D Multifocal Toric Intraocular Lenses https://ClinicalTrials.gov/show/NCT02176343 Completed Alcon Research 2014-08-22
NCT02155270 Impact of a Corneal Pre-cut on Wound Architecture and Astigmatism in Cataract Surgery - a Pilot Study https://ClinicalTrials.gov/show/NCT02155270 Completed Vienna Institute for Research in Ocular Surgery 2015-08-31
NCT02142361 Clinical Performance of Habitual Hydrogel vs. Silicone Hydrogel Toric Contact Lenses https://ClinicalTrials.gov/show/NCT02142361 Completed Coopervision, Inc. 2014-06-30
NCT02103309 Comparative Evaluation of Contact Lens Centering of DAILIES® AquaComfort Plus® Versus 1-DAY ACUVUE® MOIST® in Japan https://ClinicalTrials.gov/show/NCT02103309 Completed Alcon Research 2013-11-30
NCT02100410 On-Eye Evaluation of Contact Lens Axis Location https://ClinicalTrials.gov/show/NCT02100410 Completed Alcon Research 2013-04-30
NCT02091934 Wavefront-guided PRK vs Wavefront-optimized PRK https://ClinicalTrials.gov/show/NCT02091934 Active, not recruiting Stanford University 2017-12-31
NCT02071771 Visual Assessment of DAILIES® AquaComfort Plus® for Astigmatism as Compared to 1-DAY ACUVUE® MOIST® for Astigmatism https://ClinicalTrials.gov/show/NCT02071771 Completed Alcon Research 2014-09-30
NCT01293240 Prospective Study of Lens Performance of a Monthly Replacement Lens at Two Weeks and Four Weeks https://ClinicalTrials.gov/show/NCT01293240 Completed Alcon Research 2011-04-30
NCT01279031 Randomized Comparison of the Abbott WHITESTAR Signature System With Ellips Tranversal Ultrasound vs. the Alcon Infiniti With the Ozil Torsional Handpiece in Phacoemulsification: A Contralaterally-Controlled Trial https://ClinicalTrials.gov/show/NCT01279031 Completed Innovative Medical 2012-01-31
NCT02053688 Evaluation Study on Corneal Lens for Vision Correction https://ClinicalTrials.gov/show/NCT02053688 Completed FORSIGHT Vision3 2013-11-30
NCT02040129 Reduction of Corneal Astigmatism With Toric Intraocular Lens Implantation in Congenital Cataract https://ClinicalTrials.gov/show/NCT02040129 Completed Kyungpook National University Hospital 2009-01-31
NCT01995435 Refraction Determination Analysis https://ClinicalTrials.gov/show/NCT01995435 Completed Lee, Steven, M.D. 2015-06-30
NCT01988415 New Treatment Algorithm to Reduce Spherical Aberration After LASIK Correction for Myopia https://ClinicalTrials.gov/show/NCT01988415 Completed Abbott Medical Optics 2014-07-31
NCT01965288 Clinical Performance of Biofinity Toric Versus Air Optix for Astigmatism https://ClinicalTrials.gov/show/NCT01965288 Completed Coopervision, Inc. 2013-12-31
NCT01912781 Safety and Efficacy Evaluation of a New Contact Lens Disinfecting Solution in Gas Permeable Contact Lens Wearers https://ClinicalTrials.gov/show/NCT01912781 Completed Alcon Research 2014-05-31
NCT01912768 Safety and Efficacy Evaluation of a New Contact Lens Disinfecting Solution in Soft Contact Lens Wearers https://ClinicalTrials.gov/show/NCT01912768 Completed Alcon Research 2014-05-31
NCT01885780 Prospective Evaluation of the Effectiveness of the Femtosecond Laser-assisted Refractive Astigmatic Keratotomy. https://ClinicalTrials.gov/show/NCT01885780 Completed Technolas Perfect Vision GmbH 2014-03-31
NCT01858701 Visual Performance Investigation of Two Toric Soft Contact Lenses https://ClinicalTrials.gov/show/NCT01858701 Completed Alcon Research 2013-10-31
NCT01857102 Toric Eye Strain and Stability Study https://ClinicalTrials.gov/show/NCT01857102 Completed Johnson & Johnson Vision Care, Inc. 2014-06-30
NCT01778998 Impact of Incision Size and Architecture on Wound Stability and Astigmatism in Cataract Surgery: an Exploratory Study https://ClinicalTrials.gov/show/NCT01778998 Completed Vienna Institute for Research in Ocular Surgery 2013-09-30
NCT01763151 Comparison of Toric IOL Implantation and Opposite Clear Corneal Incision During Cataract Surgery to Correct Corneal Astigmatism https://ClinicalTrials.gov/show/NCT01763151 Completed Vienna Institute for Research in Ocular Surgery 2012-08-31
NCT01752218 A Study to Address Precision and Refractive Predictability of Femtosecond Laser-assisted Astigmatic Keratotomy Following the Cataract Surgery https://ClinicalTrials.gov/show/NCT01752218 Completed Technolas Perfect Vision GmbH 2014-04-30
NCT01699750 Comparative In-Vivo Wetting Characteristics of Silicone Hydrogel Materials With Selected Lens Care Systems https://ClinicalTrials.gov/show/NCT01699750 Completed Alcon Research 2013-11-30
NCT01699087 A Safety and Effectiveness Study of PRK Using the ALLEGRETTO WAVE® EYE-Q Excimer Laser System https://ClinicalTrials.gov/show/NCT01699087 Completed Alcon Research 2015-07-31
NCT01675492 Safety and Effectiveness of Wavefront-guided LASIK for the Correction of Mixed Astigmatism https://ClinicalTrials.gov/show/NCT01675492 Completed Abbott Medical Optics 2016-11-22
NCT01673503 A Prospective Study of Femtosecond Laser Intracorneal Lensectomi https://ClinicalTrials.gov/show/NCT01673503 Completed Odense University Hospital NA
NCT01636167 Construction of Computerized Intraoperative Keratometer and Experimental Study https://ClinicalTrials.gov/show/NCT01636167 Completed Wenzhou Medical University 2011-12-31
NCT01629693 Clinical Evaluation of Two Monthly Replacement Silicone Hydrogel Contact Lenses https://ClinicalTrials.gov/show/NCT01629693 Completed Alcon Research 2013-11-30
NCT01579045 Effect of Head and Gaze Position on Soft Toric Contact Lens Performance https://ClinicalTrials.gov/show/NCT01579045 Completed Johnson & Johnson Vision Care, Inc. 2013-03-31
NCT01552876 Comparative Clinical Evaluation of Soft Toric Lens Designs https://ClinicalTrials.gov/show/NCT01552876 Completed Johnson & Johnson Vision Care, Inc. 2012-04-30
NCT01496066 Calhoun Vision Light Adjustable Lens (LAL) in Subjects With Pre-Existing Corneal Astigmatism https://ClinicalTrials.gov/show/NCT01496066 Completed Calhoun Vision, Inc. 2016-06-30
NCT01461811 Prospective Study of an Investigational Toric Soft Contact Lens https://ClinicalTrials.gov/show/NCT01461811 Completed Alcon Research 2012-04-30
NCT01454843 LASIK Using the Alcon Allegretto Wavefront-Guided Excimer Laser vs AMO Visx Wavefront-Guided Excimer Laser https://ClinicalTrials.gov/show/NCT01454843 Active, not recruiting Stanford University 2021-12-31
NCT01362894 Clinical Comparison of Two Daily Disposable Toric Lenses https://ClinicalTrials.gov/show/NCT01362894 Completed Alcon Research 2011-08-31
NCT01348854 Safety and Effectiveness of Arcuate Incisions Performed With the iFS Femtosecond Laser System https://ClinicalTrials.gov/show/NCT01348854 Completed Abbott Medical Optics 2013-04-30
NCT04426175 Z8 OCT-controlled 2D vs 3D LASIK https://ClinicalTrials.gov/show/NCT04426175 Completed Zentrumsehstarke Hamburg 2020-04-23
NCT04345380 Rotational Stability of the Acrysof, Tecnis and Envista Intraocular Lenses https://ClinicalTrials.gov/show/NCT04345380 Completed Medical University of Vienna 2017-08-18
NCT04327518 Evaluation of the Rotational Stability of the Tecnis Toric II IOL https://ClinicalTrials.gov/show/NCT04327518 Recruiting Johnson & Johnson Surgical Vision, Inc. 2021-04-14
NCT04321226 Femtosecond Laser-assisted Astigmatism Treatment https://ClinicalTrials.gov/show/NCT04321226 Active, not recruiting Medical University of Vienna 2019-03-05
NCT04283149 Multicenter Clinical Trial of a Phakic Implantable Collamer® Lens (ICL) https://ClinicalTrials.gov/show/NCT04283149 Recruiting Staar Surgical Company 2021-01-01
NCT04208750 Clinical Investigation of the Vision-R800 Device. https://ClinicalTrials.gov/show/NCT04208750 Recruiting Indiana University 2020-11-01
NCT04111757 A Study With Technolas® TENEO 317 Model 2 Excimer Laser to Treat Participants With Myopia or Myopic Astigmatism https://ClinicalTrials.gov/show/NCT04111757 Recruiting Bausch & Lomb Incorporated 2021-02-28
NCT04072289 SMILE (Small Incision Lenticule Extraction) in the DoD (Department of Defense) https://ClinicalTrials.gov/show/NCT04072289 Recruiting United States Naval Medical Center, San Diego 2021-04-30
NCT04050605 Refitting Somofilcon A Toric Contact Lens Wearers Into Fanfilcon A Toric Lenses for 4-weeks of Wear https://ClinicalTrials.gov/show/NCT04050605 Completed Coopervision, Inc. 2019-08-16
NCT04016623 Clinical Evaluation of Invigor Toric 1-Day Contact Lenses https://ClinicalTrials.gov/show/NCT04016623 Completed Coopervision, Inc. 2019-05-15
NCT03947944 Clinical Outcomes of Small-incision Lenticule Extraction (SMILE) Using Vector Planning Method. https://ClinicalTrials.gov/show/NCT03947944 Completed Yonsei University 2019-05-07
NCT03929588 Study of a Hand-held Device Plus Mobile App Versus Standard Eye Care Devices in Measuring Refractive Error of the Eye https://ClinicalTrials.gov/show/NCT03929588 Recruiting EyeQue Corp. 2020-01-31
NCT03913338 Laser In-situ Keratomileusis With Crosslinking Compared to Conventional LASIK in Patients With High Myopia https://ClinicalTrials.gov/show/NCT03913338 Completed University Clinic Frankfurt 2018-07-03
NCT03861351 Non-comparative Trial Following Participants Implanted Bilaterally With Mini WELL Toric Ready Intraocular Lens for 6 Months After the Second Eye Implant (FUSION) https://ClinicalTrials.gov/show/NCT03861351 Recruiting SIFI SpA 2020-07-31
NCT03841253 Treatment of Vision Disturbances Due to Corneal Irregularities by Trans-epithelial Optical Phototherapeutic Keratectomy (TE-oPTK) https://ClinicalTrials.gov/show/NCT03841253 Recruiting London Vision Clinic 2021-06-01
NCT03791619 Post-Approval Study of the TECNIS SYMFONY® Toric Lenses https://ClinicalTrials.gov/show/NCT03791619 Recruiting Johnson & Johnson Surgical Vision, Inc. 2022-06-30
NCT03779503 Comparison of Two Daily Disposable Soft Contact Lenses https://ClinicalTrials.gov/show/NCT03779503 Completed Coopervision, Inc. 2019-08-26
NCT03735602 Neural Mechanisms Underlying Astigmatism https://ClinicalTrials.gov/show/NCT03735602 Recruiting Zhongshan Ophthalmic Center, Sun Yat-sen University 2021-03-31
NCT03728218 Visual Outcomes for Toric Efficacy Study https://ClinicalTrials.gov/show/NCT03728218 Recruiting University of Houston 2019-06-30
NCT03688672 Apioc Contact Lens Feasibility https://ClinicalTrials.gov/show/NCT03688672 Recruiting Lentechs, LLC 2019-06-30
NCT03684928 A Bilateral Dispensing Comparison of Comfilcon A Over Senofilcon C Contact Lenses https://ClinicalTrials.gov/show/NCT03684928 Completed Coopervision, Inc. 2018-12-14
NCT03681808 Evaluate the Safety and Effectiveness of the Biotrue ONEday for Astigmatism https://ClinicalTrials.gov/show/NCT03681808 Completed Bausch Health Americas, Inc. 2019-12-16
NCT03633851 Toric IOL vs Non-toric IOL With LRI for Corneal Astigmatism https://ClinicalTrials.gov/show/NCT03633851 Recruiting Ashford and St. Peter’s Hospitals NHS Trust 2019-08-31
NCT03610997 Photorefractive Keratectomy for Severe Anisometropia and Isoametropia Associated With Amblyopia https://ClinicalTrials.gov/show/NCT03610997 Active, not recruiting Baylor College of Medicine 2028-08-01
NCT03597906 Topography Guided LASIK by Different Protocols for Treatment of Astigmatism https://ClinicalTrials.gov/show/NCT03597906 Completed Cairo University 2019-11-15
NCT03578926 Performance of Two Toric Silicone Hydrogel Contact Lenses https://ClinicalTrials.gov/show/NCT03578926 Completed Coopervision, Inc. 2018-10-08
NCT03546647 Toric Contact Lens Performance Study https://ClinicalTrials.gov/show/NCT03546647 Completed University of Houston 2018-12-21
NCT03538964 Assessing the Astigmatism Reducing Effect With Toric IOLs in Eyeswith Low Astigmatism https://ClinicalTrials.gov/show/NCT03538964 Recruiting Vienna Institute for Research in Ocular Surgery 2020-05-02
NCT03519932 Comparison of Comfilcon A Toric Contact Lenses and Samfilcon A Toric Contact Lenses https://ClinicalTrials.gov/show/NCT03519932 Completed Coopervision, Inc. 2018-10-15
NCT03519282 Clinical Evaluation of Investigational Multifocal Toric Contact Lenses https://ClinicalTrials.gov/show/NCT03519282 Completed Coopervision, Inc. 2018-07-24
NCT03502863 Clinical Study to Evaluate Effectiveness of Digital Refraction https://ClinicalTrials.gov/show/NCT03502863 Completed Opternative 2018-07-06
NCT03418064 Performance of Toric Silicone Hydrogel Contact Lenses Following One Month of Daily Wear https://ClinicalTrials.gov/show/NCT03418064 Completed Coopervision, Inc. 2018-05-16
NCT01250964 Endothelial Cell Loss and Induced Astigmatism After Wound-directed and Wound-assisted IOL Injection https://ClinicalTrials.gov/show/NCT01250964 Completed University of North Carolina, Chapel Hill 2010-11-30
NCT01211535 Subjective Comfort With Multipurpose Care Solutions in Soft Contact Lens Wearers https://ClinicalTrials.gov/show/NCT01211535 Completed Alcon Research 2010-11-30
NCT01210820 Feasibility of iFSâ„¢ for Intrastromal Arcuate Keratotomy (ISAK) Procedures https://ClinicalTrials.gov/show/NCT01210820 Completed Abbott Medical Optics 2012-06-30
NCT01180998 Clinical Evaluation of Two Toric Contact Lenses in Current Non-toric Lens Users https://ClinicalTrials.gov/show/NCT01180998 Completed Johnson & Johnson Vision Care, Inc. 2010-10-01
NCT01140594 Wavefront-guided Photorefractive Keratectomy (PRK) Versus Wavefront-guided Lasik for Myopia https://ClinicalTrials.gov/show/NCT01140594 Active, not recruiting Stanford University 2021-12-31
NCT01140477 Toric Intraocular Lens Following Cataract Surgery https://ClinicalTrials.gov/show/NCT01140477 Completed Bausch & Lomb Incorporated 2011-12-31
NCT01135719 A Comparison of Fellow Eyes Undergoing LASIK or PRK With a Wavefront-guided Excimer Laser Versus a Wavefront-optimized Excimer Laser https://ClinicalTrials.gov/show/NCT01135719 Active, not recruiting Stanford University 2022-12-31
NCT01120782 Non-dispensing Study to Check Prescription Equivalence of Two Daily Disposable Toric Contact Lens Types https://ClinicalTrials.gov/show/NCT01120782 Completed Johnson & Johnson Vision Care, Inc. 2010-02-01
NCT01097525 Optical Quality, Threshold Target Identification, and Military Target Task Performance After Advanced Keratorefractive Surgery https://ClinicalTrials.gov/show/NCT01097525 Completed Fort Belvoir Community Hospital 2014-10-31
NCT01075542 Astigmatism Management in Cataract Surgery With the AcrySof Toric Intraocular Lens https://ClinicalTrials.gov/show/NCT01075542 Completed Maastricht University Medical Center 2012-10-31
NCT01070381 Daily Disposable Toric Comparative Trial in Europe https://ClinicalTrials.gov/show/NCT01070381 Completed Alcon Research 2010-03-31
NCT01055132 Dispensing Evaluation of New Daily Disposable Toric Soft Contact Lens. https://ClinicalTrials.gov/show/NCT01055132 Completed Johnson & Johnson Vision Care, Inc. 2010-02-28
NCT01045733 A Comparison of Corneal Aberrations in Subjects With Contralateral AcrySof IQ Toric Intraocular Lens (IOL) and AcrySof IQ IOL With Limbal Relaxing Incision (LRI) https://ClinicalTrials.gov/show/NCT01045733 Completed Alcon Research 2011-05-31
NCT01024855 Comparative Evaluation of Corneal Staining With Balafilcon A Lenses and Two Multi-Purpose Solutions https://ClinicalTrials.gov/show/NCT01024855 Completed Abbott Medical Optics 2009-06-30
NCT01018797 Intrastromal Corneal Ring for High Astigmatism on Postkeratoplasty https://ClinicalTrials.gov/show/NCT01018797 Completed Instituto de Olhos de Goiania 2009-07-31
NCT01007812 Clinical Comparison of Two Silicone Hydrogel Toric Lenses in the US https://ClinicalTrials.gov/show/NCT01007812 Completed Alcon Research 2009-11-30
NCT00978692 Toric Orthokeratology - Slowing Eye Elongation https://ClinicalTrials.gov/show/NCT00978692 Completed The Hong Kong Polytechnic University 2012-07-31
NCT00925886 Use of Toric Intraocular Lens to Neutralize Keratometric Astigmatism https://ClinicalTrials.gov/show/NCT00925886 Completed Asociación para Evitar la Ceguera en México 2009-03-31
NCT00876707 Wavefront Analyzes and Visual Performance of Three Multifocal Intra-ocular Lenses https://ClinicalTrials.gov/show/NCT00876707 Completed University of Sao Paulo 2009-11-30
NCT01432834 Efficacy of the Wavefront Optimized (WFO) Profile in Non-anterior Astigmatisms https://ClinicalTrials.gov/show/NCT01432834 Completed Democritus University of Thrace 2010-12-31
NCT00825513 Safety and Effectiveness of the Akreos Toric Intraocular Lens. https://ClinicalTrials.gov/show/NCT00825513 Completed Bausch & Lomb Incorporated 2012-03-31
NCT00821236 Contralateral Comparison of Three Excimer Laser Systems in Performing LASIK https://ClinicalTrials.gov/show/NCT00821236 Completed Durrie Vision 2010-02-28
NCT01809197 Silicone Hydrogel Contact Lens Clinical and Comfort Benefits With a Multi-Purpose Disinfecting Solution https://ClinicalTrials.gov/show/NCT01809197 Completed Alcon Research 2013-07-31
NCT03050697 Evaluation of the Safety and Performance of the HARMONI® Toric Lens https://ClinicalTrials.gov/show/NCT03050697 Completed ClarVista Medical 2017-06-07
NCT04418986 Incisional Correction of Corneal Astigmatism During Phacoemulsification https://ClinicalTrials.gov/show/NCT04418986 Completed Al-Rasheed University College 2019-09-30
NCT04210232 Post-market Study to Obtain Surgeon Feedback on Clinical Outcome in Eyes Implanted With TECNIS Toric II IOL https://ClinicalTrials.gov/show/NCT04210232 Active, not recruiting Johnson & Johnson Surgical Vision, Inc. 2021-02-28
NCT01207466 Evaluation of Two Daily Disposable Contact Lenses for Wearers With Astigmatism https://ClinicalTrials.gov/show/NCT01207466 Completed Alcon Research 2010-10-31
NCT00762502 Comparison of Senofilcon A Toric Lenses to Balafilcon A Toric Lenses Over Extended Wear Period https://ClinicalTrials.gov/show/NCT00762502 Completed Johnson & Johnson Vision Care, Inc. 2008-01-31
NCT00761826 Study of the MEL 80 Excimer Laser Using LASIK in the Treatment of Mixed Astigmatism https://ClinicalTrials.gov/show/NCT00761826 Completed Carl Zeiss Meditec, Inc. 2008-12-31
NCT00742950 Refractive Change Induced by 2.8-mm Corneal Incision https://ClinicalTrials.gov/show/NCT00742950 Completed Hospital Universitario Ramon y Cajal 2009-09-30
NCT00697190 Clinical Performance of Atypical Contact Lens Powers on Subjects With Astigmatism https://ClinicalTrials.gov/show/NCT00697190 Completed Johnson & Johnson Vision Care, Inc. 2008-09-30
NCT00663923 Comparison of Cross-cylinder and Conventional Photorefractive Keratectomy(PRK) in Correcting Medium-high Astigmatism https://ClinicalTrials.gov/show/NCT00663923 Completed Tabriz University 2009-06-30
NCT00658996 Product Performance of a Toric Contact Lens https://ClinicalTrials.gov/show/NCT00658996 Completed Bausch & Lomb Incorporated 2008-06-30
NCT00657670 Evaluation of Effectiveness of Correcting Refractive Error With Ready-made Spectacles https://ClinicalTrials.gov/show/NCT00657670 Completed Johns Hopkins University 2008-11-30
NCT00584831 Effect of Eye Movement on Toric Lens Orientation and Visual Acuity https://ClinicalTrials.gov/show/NCT00584831 Completed Johnson & Johnson Vision Care, Inc. 2008-02-29
NCT00584727 In-office Evaluation of Two Toric Soft Contact Lenses and a Spherical Soft Contact Lens https://ClinicalTrials.gov/show/NCT00584727 Completed Johnson & Johnson Vision Care, Inc. 2007-11-30
NCT00584220 Evaluation of Two Toric Soft Contact Lenses After Two Weeks of Wear https://ClinicalTrials.gov/show/NCT00584220 Completed Johnson & Johnson Vision Care, Inc. 2007-12-31
NCT00583908 Evaluation of Orientation and Visual Acuity of Four Toric Soft Contact Lenses When Head is Tilted at 90 Degrees https://ClinicalTrials.gov/show/NCT00583908 Completed Johnson & Johnson Vision Care, Inc. 2008-01-31
NCT00542581 Acrysof Toric SN60T3corneal Astigmatism Between 0.75 and 1.00 D. https://ClinicalTrials.gov/show/NCT00542581 Completed Medical University of South Carolina 2008-12-31
NCT00521833 Surgically Induced Astigmatism of Temporal Versus Nasal Clear Corneal Phacoemulsification https://ClinicalTrials.gov/show/NCT00521833 Completed Shahid Beheshti University of Medical Sciences NA
NCT00366769 Evaluation of Outcomes Following LASIK Surgery Using CustomVue https://ClinicalTrials.gov/show/NCT00366769 Completed Medical University of South Carolina NA
NCT00366743 Evaluation of Visual Outcomes After Myopic LASIK https://ClinicalTrials.gov/show/NCT00366743 Completed Medical University of South Carolina NA
NCT00366574 Comparison of a Laser Keratome to a Mechanical Microkeratome https://ClinicalTrials.gov/show/NCT00366574 Completed Medical University of South Carolina NA
NCT00365677 A Study to Investigate the Safety and Effectiveness of Aspheric Laser Refractive Surgery Treatments for Myopia https://ClinicalTrials.gov/show/NCT00365677 Completed Bausch & Lomb Incorporated 2006-03-31
NCT00365040 Customized PRK With Mitomycin Versus Customized Lasik for Myopic Astigmatism https://ClinicalTrials.gov/show/NCT00365040 Completed Federal University of São Paulo NA
NCT00348205 A Study to Evaluate the Safety and Effectiveness of the Technols 217z Zyoptix System for Hyperopia https://ClinicalTrials.gov/show/NCT00348205 Completed Bausch & Lomb Incorporated 2009-01-31
NCT00000123 The Berkeley Orthokeratology Study https://ClinicalTrials.gov/show/NCT00000123 Completed National Eye Institute (NEI) NA

Observational Studiess

#If less then 500 studies

nct_id brief_title link overall_status source primary_completion_date
NCT03299530 Accuracy of Corneal Astigmatism in Different Region Modes https://ClinicalTrials.gov/show/NCT03299530 Recruiting Wenzhou Medical University 2020-06-10
NCT03159780 Prevalence of Corneal Astigmatism Before Glaucoma Surgery in Chinese Patients With Primary Angle-closure Glaucoma https://ClinicalTrials.gov/show/NCT03159780 Completed Zhongshan Ophthalmic Center, Sun Yat-sen University 2017-08-31
NCT03097302 Tomographic Analysis of Anterior, Posterior, Total Corneal Refractive Power Changes After Laser-assisted Keratotomy https://ClinicalTrials.gov/show/NCT03097302 Completed University Clinic Frankfurt 2014-07-31
NCT02576483 An Evaluation of LASIK, SMILE and PRK Surgery in Physicians https://ClinicalTrials.gov/show/NCT02576483 Recruiting Stanford University 2025-01-31
NCT02203747 Patient Perception of Visual Distortions https://ClinicalTrials.gov/show/NCT02203747 Completed Abbott Medical Optics 2014-10-31
NCT02161263 Quality of Vision and Quality of Life With LASIK https://ClinicalTrials.gov/show/NCT02161263 Active, not recruiting Stanford University 2021-12-31
NCT02155959 Performance of a Single-piece Toric Acrylic Intraocular Lens https://ClinicalTrials.gov/show/NCT02155959 Completed Vienna Institute for Research in Ocular Surgery 2012-12-31
NCT02155556 Diurnal Changes of the Cornea - a Pilot Study https://ClinicalTrials.gov/show/NCT02155556 Completed Vienna Institute for Research in Ocular Surgery 2014-08-31
NCT01893671 Corneal Power, Astigmatism, and Aberration Changes After LASIK https://ClinicalTrials.gov/show/NCT01893671 Completed Oregon Health and Science University 2017-08-31
NCT01711190 Astigmatism Post-trabeculectomy https://ClinicalTrials.gov/show/NCT01711190 Completed Universitaire Ziekenhuizen Leuven 2012-11-30
NCT01601665 Post Approval Study of the AcrySof® IQ Toric Intraocular Lens (IOL) Models SN6AT6-SN6AT9 https://ClinicalTrials.gov/show/NCT01601665 Completed Alcon Research 2015-07-31
NCT01365728 An Outcomes Study Comparing the Intralase FS 60 to the Intralase iFS When Performing LASIK Surgery for Nearsightedness https://ClinicalTrials.gov/show/NCT01365728 Completed Stanford University 2018-12-31
NCT04393740 Contribution of Posterior Corneal Astigmatism to Total Corneal Astigmatism in a Sample of Egyptian Population https://ClinicalTrials.gov/show/NCT04393740 Recruiting Cairo University 2020-07-15
NCT04387721 Influence of Residual Astigmatism on Visual Acuity in Patients Undergoing Cataract Surgery With Trifocal Intraocular Lens Implantation https://ClinicalTrials.gov/show/NCT04387721 Recruiting Clinica Oftalmologica TACIR 2020-03-01
NCT04297969 Hyperopia Detection GCK With Glow Fixation https://ClinicalTrials.gov/show/NCT04297969 Completed Alaska Blind Child Discovery 2019-11-06
NCT04251143 Dresden Corneal Disease and Treatment Study https://ClinicalTrials.gov/show/NCT04251143 Recruiting Technische Universität Dresden 2025-12-31
NCT04249505 Refractive Accuracy of “2WIN” and Portable Autorefractors https://ClinicalTrials.gov/show/NCT04249505 Recruiting Alaska Blind Child Discovery 2020-03-31
NCT01214863 AcrySof Toric Clinical Results https://ClinicalTrials.gov/show/NCT01214863 Completed Alcon Research 2008-04-30
NCT01138189 Wavefront-guided Versus Wavefront-optimized LASIK for Nearsightedness https://ClinicalTrials.gov/show/NCT01138189 Active, not recruiting Stanford University 2022-12-31
NCT00842231 Assessment of Visual Performance in Patients With Low Levels of Astigmatism https://ClinicalTrials.gov/show/NCT00842231 Completed Alcon Research 2009-03-31
NCT03162471 How Astigmatism Influences Corneal Biomechanics and Intraocular Pressure https://ClinicalTrials.gov/show/NCT03162471 Completed Medical Universtity of Lodz 2016-12-01
NCT02023619 Corneal Epithelial and Stromal Thickness Distribution in Keratoconus https://ClinicalTrials.gov/show/NCT02023619 Completed SynsLaser Kirurgi AS 2013-09-30
NCT01978106 Comparisons of the Astigmatic Power of Toric Intraocular Lens Using Three Toric Calculators: AcrySof, TECNIS, and iTrace Toric Calculator https://ClinicalTrials.gov/show/NCT01978106 Completed Yonsei University 2013-04-30
NCT00778570 Advanced Surface Ablation (ASA) vs Laser-Assisted In Situ Keratomileusis (LASIK) https://ClinicalTrials.gov/show/NCT00778570 Recruiting Ottawa Hospital Research Institute 2020-12-31
NCT00581659 Evaluation of the Bausch & Lomb PureVision Under Nighttime Driving Conditions https://ClinicalTrials.gov/show/NCT00581659 Completed University of Iowa 2008-10-31
NCT00818532 Corneal Astigmatism Measurement Study https://ClinicalTrials.gov/show/NCT00818532 Completed Alcon Research 2009-04-30

Registries

#If less then 500 registries

nct_id brief_title link overall_status source primary_completion_date
NCT04432181 Comparison of Deviation Types Among Astigmatic Children With Or Without Amblyopia https://ClinicalTrials.gov/show/NCT04432181 Completed Sakarya University 2019-02-01